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Author

Jiaying Yin

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Open access Aug 2026

A proteome-wide association study of cardiovascular diseases in 640,000 participants of multiple ancestries

This study enables study of large-scale proteomics in diverse populations, provides a systematic map of protein associations of cardiovascular diseases, and demonstrates the utility of genetically imputed proteomes for target discovery and experimental validation.

Yu Xu, Douglas P. Loesch, H. Taylor et al. · 0 citations
#graph neural networks Open access Aug 2026

A Generative Virtual Tissue Model Enables Computational Design of Therapeutic Perturbation Strategies

Broadly, CIFM shows how generative artificial intelligence methods can be applied to model emergent behavior in highly interacting biological systems, yielding new approaches to fundamental understanding of tissue behavior as well as large-scale therapeutic design.

Yunrui Lu, Willis Zhang, Yu-Jen Chen et al. · 0 citations

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