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Jian-Guo Zhang

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Oct 2026

Preoperative Functional Imaging Predicts Deep Brain Stimulation Outcome in Craniocervical Dystonia.

BACKGROUND Deep brain stimulation (DBS) is an established treatment for craniocervical dystonia (CCD), yet postoperative benefit varies widely and cannot be estimated before surgery. Resting-state functional MRI (rs-fMRI) has shown prognostic value across DBS indications. The objective of this study was to develop and...

Hou-You Fan, A. Boutet, G. Elias et al. · 0 citations
Open access Sep 2026

Theta-frequency subthalamic nucleus deep brain stimulation selectively improves visual attention in Parkinson’s disease

Theta-frequency STN-DBS selectively improves visual attention in PD with pre-existing attentional deficits, likely by enhancing top-down attentional resource allocation, while high-frequency stimulation impairs performance.

Yue Lu, Quan Zhang, Hu-Tao Xie et al. · 0 citations
#graph neural networks Review Open access Sep 2026

Pre-operative neural substrates of deep brain stimulation outcomes: A systematic review and cross-disorder network synthesis.

BACKGROUND Deep brain stimulation (DBS) is an established therapy for movement and psychiatric disorders, yet its effects vary substantially across individuals. The pre-operative brain provides the individual circuitry upon which DBS acts, but how this circuitry shapes surgical outcomes remains poorly characterized....

Yu-Tong Bai, Tiffany A. Rodrigues, Andrew Z. Yang et al. · 0 citations
Open access Aug 2026

Direct Substantia Nigra Deep Brain Stimulation in Parkinson's Disease: Efficacy, Safety, and the Frequency-Response Relationship.

Direct SN stimulation produced a clear frequency-dependent acute response in PD, with 130 Hz yielding the strongest motor and spatial gait benefits among the tested frequencies and effects of similar magnitude to standard STN stimulation.

Yu-Ye Liu, Chenguan Jiang, Bing-Xin Li et al. · 0 citations

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