Abstract Background The nomenclature change from non-alcoholic fatty liver disease to metabolic dysfunction-associated steatotic liver disease (MASLD) better encapsulates the associated metabolic milieu. While MASLD is associated with increased heart failure (HF) risk, characteristics and outcomes of MASLD in patients...
N. Chew, Chandramouli Chanchal, W. Tay et al.· Open Heart· 0 citations
Inflammation plays a central role in the pathophysiology of heart failure (HF), and contributes to disease progression, morbidity and mortality. However, the relationships between inflammatory cytokines and different HF subtypes are complex, heterogeneous and bidirectional. In this review, we examine inflammatory pathw...
G. Mendieta, Gianluigi Pironti, Jasper Tromp et al.· Cardiovascular Research· 0 citations
The HFA-PEFF and H2FPEF scores based on automated and manual echocardiographic analysis showed similar diagnostic accuracy, suggesting automated HFpEF diagnosis using deep learning analysis of echocardiograms is feasible.
C. Venema, M. Venner, A. Achten et al.· European Heart Journal - Dig...· 1 citation
Body mass index (BMI) and waist-based anthropometric indices are widely used to estimate adiposity and cardiometabolic risk. Yet in established heart failure (HF), modestly higher BMI is associated with improved survival, while waist-based measures show a linear association with worse outcomes. This apparent discrepanc...
C. C. S. van der Hoef, J. T. ter Maaten, L. Meems et al.· Journal of Cardiac Failure· 0 citations
Heart failure with preserved ejection fraction (HFpEF) prevalence is increasing in Asia, driven by aging populations and rising cardiometabolic risk. Asian patients with HFpEF present a decade earlier than Western counterparts, carry a disproportionate burden of diabetes, chronic kidney disease, and visceral adiposity...
Jasper Tromp, T. Teng, Wan T. Tay et al.· JACC: Asia· 0 citations
Mechanistically, visceral adiposity, systemic inflammation, immunometabolic dysregulation, structural remodeling, and accelerated cardiac aging converge to drive HFpEF across Asian patients, often at lower body mass index thresholds than recognized in Western models.
E. Balasa, F. Capone, A. Vacca et al.· 0 citations
Mechanistically, visceral adiposity, systemic inflammation, immunometabolic dysregulation, structural remodeling, and accelerated cardiac aging converge to drive HFpEF across Asian patients, often at lower body mass index thresholds than recognized in Western models.
E. Balasa, F. Capone, A. Vacca et al.· JACC: Asia· 0 citations
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