Abstract Co‐occurrence of child and adolescent neurodevelopmental and mental health conditions is the rule rather than the exception, yet translating this insight into shared frameworks and clinical practice remains challenging. In this Editorial, we are pleased to introduce the 26 papers included in the 2026 Special Issue of JCPP Advances. This Special Issue aimed to advance our understanding of transdiagnostic mechanisms, dimensions, and practices in child and adolescent mental health, and includes original articles, reviews, commentaries, and an editorial perspective. Collectively, these articles illustrate three main ‘transdiagnostic’ conceptualisations; (i) mechanistic approaches identifying shared biological, cognitive, or affective processes across diagnostic boundaries; (ii) dimensional approaches mapping symptom covariance onto hierarchical structures such as the general ‘p’ factor and internalising, externalising, and neurodevelopmental spectra; and (iii) developmental, clinical‐staging approaches treating early, non‐specific features as precursors to a broad range of later outcomes. Methodologically, the current Special Issue highlights both the opportunities and limitations of large existing datasets, multi‐informant assessment, and neuroimaging and genomic approaches, while underscoring the persistent difficulty of modelling transdiagnostic dimensions developmentally. Importantly, while translation into routine clinical care remains limited, the field is now well positioned to test the clinical utility and effectiveness of transdiagnostic dimensional assessments and interventions in routine care.
Persistent comorbidity, diagnostic instability and the scarcity of disorder-specific causes have encouraged the proposal that a single superordinate dimension underlies liability to all common mental disorders. This proposition, expressed empirically as the general factor of psychopathology and framed conceptually as a...
Luiz Costa, Fernando Martins Castanheira, Giovanna Azevedo Rodrigues et al.· International Neuropsychiatr...· 1 citation
This paper reviews five interconnected domains of youth mental health: depression and anxiety, school based mental health systems, suicide prevention, digital mental health interventions, and the relationship between trauma exposure and resilience and concludes with implementation priorities for resource constrained se...
B. Imtiaz· Pakistan Journal of Positive...· 0 citations
INTRODUCTION
Psychiatric biomarker research has traditionally been organized around diagnostic categories, but clinical heterogeneity, comorbidity and shared biological mechanisms across psychiatric conditions have increased interest in transdiagnostic approaches. These approaches may be especially relevant for early r...
Katelyn Hummel, Luigi Boccuto, Sara M. Sarasua et al.· Early Intervention in Psychi...· 0 citations
In this special issue, we bring together a set of studies that collectively demonstrate the power of temperament-based frameworks for advancing understanding of the structure of psychopathology and its underlying mechanisms, particularly in domains marked by substantial heterogeneity, comorbidity, early emergence, and...
S. Karalunas, E. D. Musser, K. Pérez-Edgar· Clinical psychological scien...· 0 citations
Abstract Children with disabilities and chronic diseases experience intersecting health, developmental, psychosocial, educational, environmental, and family challenges, but their clinical trajectories and service needs are not interchangeable. This Guest Editorial accompanies the article collection “Children with Disab...
S. Abuhammad· Journal of Multidisciplinary...· 0 citations
Abstract Background Clinicians across disciplines use the Diagnostic and Statistical Manual of Mental Disorders (DSM) to describe, diagnose, and plan treatment for mental health conditions. This means that future iterations of the DSM need to incorporate information that captures diverse expressions of symptomatology a...
D. Clarke, L. Yousif· International Journal of Neu...· 0 citations
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