Addressing the multifaceted diagnostic and pharmacotherapeutic challenges of OABD through dedicated age-specific clinical trials, comparative effectiveness studies, systematic evaluation of deprescribing strategies, and enhanced clinician awareness will be fundamental to improve outcomes for this understudied and expanding population.
This review summarizes the current clinical pharmacology of bipolar disorder, emphasizing mechanisms of action, pharmacokinetic and pharmacodynamic properties, efficacy, safety, and monitoring requirements of established and emerging pharmacological treatments.
Michel Bourin· Journal of Psychology and Ps...· 0 citations
Abstract Objective Bipolar disorder affects approximately 1% of the population, although some studies report prevalence rates of up to 6%. Distinguishing it from unipolar depression remains challenging, with diagnostic delays often exceeding ten years. This systematic review aims to identify clinical and historical fea...
Docteur Scheherazade Niktabe, Catherine Massoubre· European Journal of General...· 0 citations
Abstract Background Panic disorder (PD) and generalized anxiety disorder (GAD) significantly impair daily functioning and cause substantial emotional distress, necessitating active and timely treatment. Although selective serotonin reuptake inhibitors and serotonin–norepinephrine reuptake inhibitors are first-line phar...
E. Moon, J. Seo, M.-K. Kim et al.· International Journal of Neu...· 0 citations
BACKGROUND
Bipolar disorder is a disabling psychiatric condition affecting approximately 2% of the population, for which identifying modifiable risk factors prior to illness onset is a research priority. Cannabis use is highly prevalent, yet its role in the development of bipolar-spectrum outcomes remains unclear. Prev...
Cecilia Sanjuan-Ortiz, Paula Querol, C. Aymerich et al.· Journal of Affective Disorde...· 0 citations
Current evidence suggests that LOBD likely represents a heterogeneous condition with multiple underlying mechanisms, including vascular burden, neurodegenerative processes, and age-related biological vulnerability, including vascular burden, neurodegenerative processes, and age-related biological vulnerability.
Bruno Lancksweerdt, A. Van Duyse, B. Sabbe· Expert Review of Neurotherap...· 0 citations
Introduction: Bipolar disorder is a chronic psychiatric condition characterized by recurrent episodes of mania, hypomania, and depression. Maintenance pharmacotherapy aims to prevent recurrence, reduce hospitalization, and preserve psychosocial functioning. Lithium and quetiapine are among the pharmacological options u...
Aileen Aurellia· Journal of Psychiatry Psycho...· 0 citations
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