AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
TL;DR
It is proposed SLC25A1 is associated with metabolic reprogramming in HCC and contribute to tumor progression by promoting lipogenesis and offering a promising therapeutic target for early intervention and treatment.
Hepatocellular carcinoma (HCC) poses a significant global health burden with limited therapeutic options, particularly for non-viral etiologies. The mitochondrial solute carrier SLC25A43 is implicated in cellular redox homeostasis, yet its role in HCC remains unclear. This study aimed to comprehensively investigate the...
It is demonstrated that SLC25A20 is significantly upregulated in lung adenocarcinoma (LUAD) tissues and cells, and its expression correlates with poor patient survival, and it is suggested that it may be a therapeutic target.
High MCT4 expression in TAMs may be associated with metabolic reprogramming toward glycolysis, and could promote M2 polarization of TAMs, thereby contributing to HCC progression and poor clinical outcomes.
It is suggested that TALDO1 may serve as a key molecule linking metabolic abnormalities to immune microenvironment remodelling and may have potential therapeutic significance.
This review summarizes essential steps in glucose and lipid metabolism to distinguish similarities in glucose and energy metabolism reprogramming from divergent lipid remodeling in different types of primary liver cancers and shows the convergent nature of metabolic alterations in glucose decomposition and related mito...
Functional enrichment analysis reveals that SLC25A39 is commonly associated with immune-related pathways and cell cycle-related pathways in the pan-cancer dataset.
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