Biomimetic Nanocarriers Based on Cell Membranes for Precision Drug Delivery: Advances, Applications, and Translational Challenges

Biomimetic cell-membrane-coated metallic nanoparticles in cancer therapy: Design, functional mechanisms, and translational challenges.

Cancer remains a major health concern worldwide, with the need to identify better and more specific treatment measures. The concept of using metallic nanoparticles in drug delivery has attracted significant attention due to their distinct physicochemical characteristics, including surface area, size, and multifunctiona...

Chitosan-based nanoplatforms for biomedical theranostics: Recent advances in design, functionalization, and applications

Extracellular vesicles in targeted drug delivery: from biological functions to surface engineering

The application of engineered EVs in the treatment of several pathological conditions, including cardiovascular, neurological, autoimmune, and cancer diseases, are summarized, and the major challenges in clinical translation and future perspectives for EV-based targeted therapies are discussed.

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

This review provides a biologically informed roadmap for designing efficient gene delivery vectors, proposing membrane-integrated nanovesicles (NVs) as "living interfaces" for non-viral gene therapy.

Recent advances in hybrid membrane vesicles as programmable biomimetic drug delivery.

Biomimetic nanomedicine utilizing cell membrane cloaking has emerged as a promising approach to enhance nanocarrier performance by integrating the physicochemical benefits of synthetic nanoparticles with the biological functionalities of source cells. Nonetheless, single-source membrane systems are inherently limited b...

Nanomaterial-based drug delivery systems: From intelligent delivery to clinical translation and precision nanomedicine.

A structured translational roadmap is proposed that prioritizes biologically predictive design, fit-for-purpose safety assessment, scalable good manufacturing practice production, early regulatory alignment, and clinically meaningful benefit over unnecessary structural complexity.