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Tunable polymers for polymer–lipid hybrid nanoparticles facilitate controlled organ-selective RNA delivery

Xu Wang Ze-Ru Tian Alexis Pacheco Benitez Xiaoyan Bian Amogh Vaidya Erick D. Guerrero Ye-Hui Sun Chu-Han Zhang Yaou Duan Jingwen Wei Yujin Kim Yu-Fen Xiao Priyanka Patel D. Siegwart
Aug 2026 · Nature Chemical Engineering · Vol 3, pp. 443 - 459 · 0 citations · 63 references

TL;DR

This work advances chemical engineering strategies for RNA delivery by integrating materials design, molecular transport optimization and scalable nanoparticle synthesis, contributing to the broader development of biomolecular and polymer engineering solutions for therapeutic production and application.

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