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Erratum: Resolution of hepatic fibrosis after ZFN-mediated gene editing in the PiZ mouse model of human α1-antitrypsin deficiency.

Aug 2026 · Hepatology Communications · Vol 10 9 · 0 citations · 1 references
Medicine
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#gene editing Review Sep 2026

Unlocking non-model organisms with CRISPR-Cas: A roadmap for sustainable biotechnology.

It is concluded that bridging the gap between foundational CRISPR research and its real-world applications is imperative and future efforts should focus on democratizing tools via open-source platforms, advancing delivery systems, and fostering sustainable innovation through synthetic biology integration to fully realize the transformative potential of genome editing in organisms beyond model organisms.

S. Sarsaiya, Archana Jain, Jishuang Chen et al. · 2 citations
#gene editing Aug 2026

CRISPR/Cas9-Mediated Site-Directed Mutagenesis of Genes in Klebsiella pneumoniae.

This protocol minimizes off-target editing, shortens experimental timelines, reduces screening workload, and provides a reliable platform for investigating resistance mechanisms, validating candidate genes, and supporting functional genomics studies in clinically relevant bacterial pathogens.

Liu Chun, Zhang Quan, Matas Ke · 0 citations
#gene editing Open access Aug 2026

Virus-like particles enable targeted gene engineering and pooled CRISPR screening in primary human myeloid cells.

A virus-like particle (VLP)-based toolkit that delivers diverse CRISPR editing modalities to human monocytes, macrophages and dendritic cells with high efficiency while preserving viability and innate immune responsiveness is presented.

Hyuncheol Jung, Pascal Devant, Carter Ching et al. · 0 citations
#gene editing Open access Aug 2026

CRISPR/Cas9-Mediated Disruption of Duplicated Sizzled Genes Induces Twin-Tail-like Caudal Bifurcation in Goldfish (Carassius auratus)

Findings provide direct functional evidence that szl regulates median caudal patterning in goldfish and suggest that szl-dependent modulation of the Chordin/BMP network can generate twin-tail-like caudal morphology.

Huijuan Li, Xiaoying Zhang, Xiaowen Wang et al. · 0 citations
#gene editing Review Open access Aug 2026

Induced pluripotent stem cell reprogramming: methodological evolution and challenges in clinical translation

This review summarizes the trajectory of iPSC reprogramming technologies and identifies the core “translational triltrilas”, namely, the inherent tradeoffs between security, homogeneity, and scalability, and proposes a comprehensive strategy to overcome these bottlenecks.

Mengmeng Chen, Ning Zuo, Qi Wang et al. · 0 citations

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