Mechanistic insights into gelation and rheological behavior of Pluronic F127-based thermoresponsive hydrogels

How Gellan gum gelation is affected by acyl substituents: from hierarchical organization to simple viscoelastic behavior.

Gellan gum, a linear anionic exopolysaccharide, is widely employed as a gelling agent owing to its biocompatibility and tunable rheological properties. Its degree of acylation determines high acyl (HA-Gg) and low acyl (LA-Gg) forms, yielding hydrogels with different chemical-physical properties. Rheological measurement...

An Injectable, Self-Healing Hydrogel Based on G-Quadruplexes/Phenylboronic Acid Composites with Antibacterial Activity

The injectable, self-healing G-quadruplex hydrogel constructed in this study integrates a porous architecture, dynamic reversibility, and robust biological functionality, highlighting its promising potential in antibacterial applications.

Spontaneous Phase Separation Enables Rapid, Polymerization-Free Fabrication of Gels.

Hydrogels are cross-linked polymeric networks with wide applications in drug delivery, tissue engineering, biosensing, and environmental remediation. These hydrogels additionally host living cells, small molecules, and biological propagules, which further expand the applications of these materials. However, most, if no...

Structural reinforcement of Pluronic F127/chitosan thermoresponsive hydrogels through polydopamine incorporation for controllable drug transport.

Results establish PDA-mediated non-covalent reinforcement as an effective crosslinker-free strategy for engineering thermoresponsive hydrogels with tunable network mechanics and controllable NIR-responsive drug transport for localized chemo-photothermal therapy.

Tunable Sol-Gel Transition in Poloxamer Blends for Injectable Osteoarticular Applications.

The results show that careful selection and optimization of poloxamer blends allow tailoring material properties for specific biomedical functions, and make them practical for further development in injectable biomaterials and drug delivery systems for osteoarticular repair.

Self-Degradable Temporary Plugging Agent Based on Dynamic Covalent Bond-Crosslinked Double-Network Hydrogels