CatESO: Differentiable Enzyme Sequence Optimization Guided by Substrate-Aware kcat Prediction Zhenjia Gan Yuzhi Xu Junde Xu Zhihao Wu Juping Huang Jiabin Yin Guangyong Chen J. Zhang Jul 2026 · bioRxiv · 0 citations · 97 references Biology DOI Semantic Scholar Save View source Cite Copy APA Copied ✓ Copy MLA Copied ✓ Copy BibTeX Copied ✓ Share