Urolithin A Exerts Neuroprotective Effects Against Ischemic Stroke by Inhibiting Oxidative Stress and Neuroinflammation

Downregulation of Lgals3 Alleviates Inflammatory Response and Apoptosis in a Mouse Model of Cerebral Ischemia/Reperfusion Injury

The present work investigated the expression and function of Lgals3 in cerebral ischemia/reperfusion (cerebral IR) injury.

RETRACTED: NaHS Protects against the Impairments Induced by Oxygen-Glucose Deprivation in Different Ages of Primary Hippocampal Neurons

Paeonol as a Multi‐Target Therapy for Neurological Disorders: Mechanistic Insights Into Neuroprotection

Neurological disorders are a major global health challenge in the current era, and they need new therapeutic treatments.

Cholesterol Drives IFITM3 + Microglia Activation and Induces STING Mediated Neuroinflammation After Ischemic Stroke

Cerebral ischemic stroke triggers extensive neuronal membrane breakdown, releasing a massive load of cholesterol that overwhelms resident microglia. Dysregulated microglial cholesterol metabolism has been implicated in post‐stroke neuroinflammation, yet the specific pathogenic microglial subpopulations, their molecular...

Editorial for the Special Issue “Molecular Mechanisms and Treatment of Ischemia–Reperfusion Injury”

Ischemia-reperfusion injury (IRI) remains one of the most challenging obstacles in modern medicine, influencing outcomes across cardiovascular disease, organ transplantation, stroke, peripheral ischemia, and acute surgical conditions [...].

Scutellarin Alleviates Neuronal Apoptosis After Ischemia and Hypoxia via the HIF‐1α–CX3CR1 Axis

Stroke is a significant health threat characterized by high incidence, mortality, disability, recurrence, and complications. Over 70% of strokes are ischemic in nature. Reducing neuronal apoptosis following ischemic–hypoxic injury is crucial for effective treatment. This study investigates the direct neuroprotective ef...