Protection against severe disease and real-world VE studies from the Omicron era further indicated comparable or improved protection against hospitalization and severe outcomes with heterologous boosting compared to homologous combinations.
An outbreak of Ebola disease caused by Bundibugyo virus (BDBV) has been ongoing since April 2026, primarily in the Democratic Republic of the Congo. We estimated the initial reproduction number of BDBV at 1.85 (95% CrI: 1.09, 3.25), underscoring the urgent need for timely implementation of control measures to prevent w...
Zihao Guo, Yong-Di Yu, Zhao-Jun Ding et al.· Journal of Travel Medicine· 0 citations
As the Bundibugyo Ebola virus outbreak continues to spread in the Democratic Republic of the Congo, the first of four vaccine candidates has entered clinical trials. Katharine Lang reports on what is known about them and the UK’s key role in the trials
Katharine Lang· British medical journal· 2 citations
In June 2026, an intensive care physician deployed in the Democratic Republic of the Congo and previously vaccinated against Ebola virus developed fatigue, nausea and headaches while returning to France. Bundibugyo virus was identified with RT-PCR. The patient was treated with remdesivir and recovered fully. Contact tr...
M. Mailhe, D. Pannetier, Estelle Yamani et al.· Euro surveillance : bulletin...· 0 citations
Ebola virus disease and Marburg virus disease are severe, highly lethal infections caused by filoviruses, characterized by rapid transmission, complex clinical management, and major socio-economic impact. A narrative review of recent outbreaks between 2021 and 2025 underscores persistent systemic gaps that compromise e...
H. O. Chitumba· Journal of Infection in Deve...· 0 citations
An uncontrolled and rapidly growing outbreak of Bundibugyo virus (BDBV) is currently gripping the Democratic Republic of the Congo and threatening health security across Central Africa. There are no available BDBV-specific vaccines, although emerging evidence suggests that the Ebola virus-specific vaccine, rVSV-EBOV (a...
J. Wight, Guodong Liu, Michael Chan et al.· bioRxiv· 1 citation
The ongoing 2026 outbreak of Bundibugyo virus (BDBV) in the Democratic Republic of the Congo and Uganda is the largest so far on record. Despite experience from previous Ebolavirus outbreaks, the current lack of vaccines against BDBV underscores a recurring failure in proactive preparedness. Here, we explore the most p...
M. Pletschette, Nadine Biedenkopf· npj Vaccines· 0 citations
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