Jun 2026· Science China Life Sciences· 0 citations· 591 references
Medicine
TL;DR
The roles and molecular mechanisms of diverse RNA types, the roles of RNA structures and modifications in regulatory processes, and the translational application of RNA-based strategies for improving agronomic traits are discussed.
The regulatory functions of bacterial sRNAs are summarized, the molecular mechanisms that govern their expression and regulatory consequences are described, and the many exciting open questions surrounding sRNA-mediated gene regulation in bacteria are discussed.
Kai Papenfort· Nature Reviews Microbiology· 2 citations
Cells in multicellular eukaryotic systems are diverse biological units, with characteristics and functions determined by their molecular profiles. CRISPR–Cas9 genome editing has been widely used across biology to modulate gene expression and study gene function. However, there is currently no versatile and scalable met...
Arman Adel, Yuta Shuto, Shunsuke Kawasaki et al.· bioRxiv· 0 citations
A critical assessment of the molecular regulatory networks involving ncRNAs in plants is provided, thereby offering a realistic foundation for future translational applications in agriculture and forestry.
Q. Wu, L. Zhou, X. Pan et al.· Russian journal of plant phy...· 0 citations
This chapter describes the design of cgRNAs and provides detailed protocols for their in vivo characterization in E. coli, and shows how cgRNAs can be integrated into endogenous gene circuits to achieve sophisticated and logical regulation of gene expression.
Dongwon Park, Woosub Shin, Hansol Kang et al.· Methods in molecular biology· 0 citations
The latest functional genomics strategies used to examine NCRNAS are discussed and their transformative ability in accurate therapy is highlighted, highlighting their transformative ability in accurate therapy.
Deepak Kumar Sahu, Harish Jaiswal· Research journal of biotechn...· 0 citations
How splicing-dependent and splicing-independent activities are integrated are discussed and a framework in which splicing factors act as regulatory hubs coordinating gene expression across multiple layers is proposed.
M. J. Iglesias, Y. Agrofoglio, Lukasz Szewc et al.· TIBS -Trends in Biochemical...· 0 citations
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