TL;DR
The potential of exosome-biomimetic nanoparticles for their use as drug carriers to improve the efficacy of anticancer therapy is highlighted.
Exosomes have the potential to become next-generation delivery systems that revolutionize cancer therapy and regenerative medicine treatment approaches with further development.
Exosomes are biological nanoparticles (30-150 nm) secreted by most eukaryotic cells. They are composed of a lipid bilayer membrane and an inner compartment that stores various cellular components. In recent years, research on exosomes has grown exponentially due to their biocompatibility, low immunogenicity and cytotox...
Exosomes are an evolved sub-type of extracellular vesicles (EVs) that have gained popularity in recent years as a novel biological nanocarrier system for targeted precision therapy in cancer owing to their excellent biocompatibility, low immunogenicity, and high stability. While other artificial systems can only delive...
Novel NCs like microemulsions, vesicular (liposomes), and nanoparticular NCs are created and explored, which have unique improved penetration and retention in the tumour tissue.
ABSTRACT Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are lipid bilayer-bound nanoparticles secreted by various cell types. EVs mediate intercellular communication by selectively transporting bioactive molecules including proteins, lipids, and nucleic acids. This review compreh...
Practical guidelines for the rational design and standardization of EV-INP hybrids toward intelligent nanomedicine are provided, with particular emphasis on comparable metrics and quality assurance.
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