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[Construction of a chimeric cell model expressing human immunodeficiency virus-1 envelope protein based on transposon system and evaluation of chimeric antigen receptor t-cell cytotoxicity in vitro].

Jiarui Liu Yang Gao Changjun Wang Lei Yu Yan Ma Mengying Zhou Ying Zhou Siqi Yang Jiezhen Li Chaojiang Gu Shasha Zhao
Jul 2026 · Sheng wu gong cheng xue bao = Chinese journal of biotechnology · Vol 42 7, pp. 3203-3216 · 0 citations
Medicine

TL;DR

The HEK293T model stably expressing membrane-anchored HIV-1 gp160(ΔCT) model provides a robust platform for benchmarking the targeted recognition and cytotoxic activity of antiviral antibodies, agents, and CAR-T therapies in HIV research.

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