Cytotoxic CD4+ T cells support age-associated myelopoiesis

TNFR1 expression on cancer cells mediates immune escape and an immunosuppressive microenvironment

Evidence is provided for a key role of TNFR1, as expressed by malignant cells, in orchestrating a pro-tumor immunosuppressive environment through secondary inflammatory mediators through secondary inflammatory mediators.

CD8+ T cells kill tumors by proxy

Good neighbors make lasting memory

Naive T cell decline limits cancer immunity in middle-aged male mice

Microbial cues for a stem-like lymphoid niche.

While tertiary lymphoid structures (TLSs) broadly correlate with immunotherapy efficacy, their functional heterogeneity can translate into divergent clinical outcomes. In this issue of Cancer Cell, Hu et al. uncover a microbiota-orchestrated stem-like lymphoid niche in which CD70+ ILC2s sustain progenitor exhausted T c...

Correction: Natural killer (NK) cells with downregulated activating receptors and IL-10 production promote Trypanosoma cruzi T-cell responses in subjects in the Chronic phase of Trypanosoma cruzi infection: An exploratory immunological analysis

[This corrects the article DOI: 10.1371/journal.pntd.0014622.].