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A human monoclonal antibody from hybrid immunity exhibits exceptional neutralization breadth against antigenically divergent contemporary Omicron JN.1 lineage variants

Diwakar Rathour Shweta Shrivas Naresh Kumar Chaman Prasad Janmejay Singh G. Singh A. Surendranath Shweta Rathi Sneha Verma Supriya Chauhan Balwant Singh Jyoti Sutar S. Chattopadhyay G. Batra Sudipta Sonar Isabella Eckerle Lorenzo Subbissi A. Mohan Shailendra Asthana Suprit Deshpande Jayanta Bhattacharya

Jul 2026 · bioRxiv · 0 citations · 25 references

Biology

TL;DR

It is found that among individuals with hybrid immunity who developed robust, durable antigen-specific antibody responses, one developed antibody response capable of broadly cross-neutralising contemporary Omicron variants.

DOI Semantic Scholar

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