An extensive analysis of the physical principles of blood composition detection technologies based on optical biosensors and their role in modern medical diagnostics contributes to the development of advanced diagnostic systems and improvement of clinical monitoring efficiency.
CARMEN is introduced, a polycistronic fluorescence-based biosensor system that enables simultaneous, high-resolution monitoring of Ca 2+ signals in distinct subcellular compartments within the same living cell, supporting future high-content imaging and drug-screening applications.
A molecularly imprinted g-C3N4/MXene/AuNPs photoelectrochemical sensor was developed for non-invasive sweat lactate detection, achieving a linear range of 1-20 mM and a detection limit of 0.55 mM. Reliable on-body analysis demonstrates its potential for fitness assessment and metabolic monitoring.
Xin-Jun Hu, Ji-Han Liu, Jia-Yi Zhao et al.· Chemical Communications· 0 citations
Biosensors based on chemiluminescence (CL) and electrochemiluminescence (ECL) have demonstrated high sensitivity for the detection of cancer biomarkers, including proteins, nucleic acids, extracellular vesicles, exosomes, intact tumor cells, and circulating...
A. Bhat, S. Fuloria, Riya Thapa et al.· Analytical Methods· 0 citations
A new sensing strategy is reported, which reads signals from individual camera images without the need for a spectrometer, which enables the label-free detection of biomarkers in a handheld format.
This work describes a label-free colorimetric immunoassay that initially integrates rolling circle amplification (RCA) with Tyndall effect (TE) characteristics of nucleic acid colloids. Using only a laser pointer and a smartphone, it achieves instrument-free protein quantification with 13-fold higher sensitivity than t...
Jia-Rui Li, Wen-Li Zhu, Karuna D. Chen et al.· Chemical Communications· 0 citations
Light-based biomedical sensing and therapy enables highly precise, timely and contactless interventions and range from neuronal stimulation via optogenetics over sensing cellular activity by functional fluorescence to monitoring health signals using wearable devices. Organic semiconductors are ideally suited building b...
Caroline Murawski, Giuseppe Ciccone, Simon Letzer et al.· Organic and Hybrid Light Emi...· 0 citations
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