Design to Neuroprotection: A Blood Brain Barrier Permeable Selective HDAC3 Inhibitor Active against Chemical and Viral Insults
Darakhshan Begum
Sanjeev Regula
Suryansh Sengar
S. Amin
Dharani Sen
Swati Biswas
S. Gayen
Vivek Sharma
B. Ghosh
Abstract
Neuronal loss in neurodegenerative diseases is mediated by oxidative stress, neuroinflammation, and epigenetic dysregulation, with histone deacetylase 3 (HDAC3) playing a central role in inflammatory signaling and neuronal damage. We...