This work investigated associations of seven plasma essential trace elements, including manganese, iron, cobalt, copper, zinc, selenium, and molybdenum, with AD and all‐cause dementia risk.
Abstract
Dysregulation of essential trace elements has been implicated in Alzheimer's disease (AD) pathogenesis, yet comprehensive epidemiologic evidence remains limited. We investigated associations of seven plasma essential trace elements, including manganese, iron, cobalt, copper, zinc, selenium, and molybdenum, with AD and all‐cause dementia risk.
The impact of CKD transcriptional risk on AD endophenotypes is assessed by assessing the impact of CKD transcriptional risk on AD endophenotypes in individuals with chronic kidney disease.
Jung-Min Pyun, Young Ho Park, Jiyun Hwang et al.· Alzheimer's & Dementia· 0 citations
Developmental neurotoxicant exposures (e.g., lead [Pb]) are suspected contributors to dementia. Dementia is characterized by amyloid beta (Aβ) plaques and dysregulated metabolism. To better understand the relationship between environment and dementia risk, we assessed the impact of perinatal Pb exposure on dementia‐rel...
Rachel K. Morgan, Evelyn K. Matei, Junru Pan et al.· Alzheimer's & Dementia· 0 citations
Apolipoprotein E (APOE) ε4 is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD), but its contribution to disease pathogenesis remains incompletely understood.
A. Shvetcov, Shannon Thomson, Mark E. Graham et al.· Alzheimer's & Dementia· 1 citation
