A dual-view approach that connects clinical practice with computational methods is presented, establishing a five-level competency scheme following Miller’s Pyramid and linking deductive, inductive, and abductive reasoning patterns to common medical goals and tasks.
Abstract
Large language models (LLMs) have emerged as important tools in healthcare, showing growing potential for clinical reasoning and patient care. This survey examines recent progress in medical LLMs, focusing on reasoning applications and requirements. We present a dual-view approach that connects clinical practice with computational methods. On the clinical side, we establish a five-level competency scheme following Miller’s Pyramid, progressing from knowledge recall to dynamic case management. On the computational side, we link deductive, inductive, and abductive reasoning patterns to common medical goals and tasks. We also introduce a benchmark dataset spanning five levels of medical reasoning capability and report results on 18 state-of-the-art models, revealing that medical specialist models excel in diagnosis-centric tasks while general models lead in decision support and dialogue. We conclude by discussing current progress and open challenges, including data limitations, hallucination, and grounding issues, and outline directions toward safer, more reliable, and more workflow-ready systems.
This review provides a structured overview of recent progress in Med-LLMs by examining their major application areas, key challenges, and emerging future directions.
Yuyang Sha, Li Yu, Zejia Lin et al.· Military Medical Research· 0 citations
This entry-level tutorial aims to equip healthcare professionals with the tools necessary to effectively integrate LLMs into clinical practice, ensuring that these powerful technologies are applied in a safe, reliable, and impactful manner.
Qiao Jin, Nicholas Wan, Robert Leaman et al.· Nature Protocols· 1 citation
Uncommon and off-guideline cases are difficult for clinical decision support, because physicians must make a series of management decisions under diagnostic uncertainty and rarely see the full case at once. Most large language model (LLM) benchmarks for medicine score only the final diagnosis, yet much of clinical care...
Ofir Ben Shoham, O. Perets, Nir Grinberg et al.· 0 citations
A scoping review of 24 PubMed-indexed studies published between 2023 and 2026 was conducted to assess current applications, benefits, limitations, and future directions of LLMs in healthcare.
Antoni Klamka, Paulina Kawalec, Kamil Bronikowski et al.· Quality in Sport· 0 citations
IMCBench is introduced, an image-grounded, multi-turn medical conversation benchmark that pairs real, publicly available clinical images with synthetic patient profiles to simulate realistic patient-clinician interactions and demonstrates that accurate clinical description does not guarantee safe patient guidance, moti...
Maria Xenochristou, Ashutosh Joshi, Korosh Vatanparvar et al.· arXiv.org· 0 citations
Medical Question Answering (MQA) has emerged as a critical artificial intelligence (AI) capability for supporting clinicians, researchers, and the general public with timely and evidence-based responses to medical queries. Recent advances in natural language processing (NLP), computer vision, and large language models...
Eya Mhedhbi, Xiang Zhu, Muhammad Ayaz et al.· Computer Methods and Program...· 0 citations
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