Multiple-choice medical benchmarks are increasingly saturated, and recent rubric-based evaluations such as HealthBench have shown that open-ended clinical performance is far from solved - its"Hard"subset top score remains 32%. We present a small, deliberately difficult evaluation dataset of five clinician-authored clinical scenarios spanning four specialties (anaesthesia, internal/family medicine, emergency medicine, and obstetrics), each accompanied by an atomic, weighted, MECE rubric (25-62 criteria per task; 184 criteria total) authored from a clinician-drafted golden answer. We evaluate three frontier models: GPT 5.4, Claude Opus 4.7, and Gemini 3.1 Pro. Mean rubric pass rates were 0.47 (Claude), 0.39 (GPT), and 0.37 (Gemini). The central finding is an inversion of clinical priority: the highest-weighted (weight-5, critical) criteria passed at only 32.4-41.7%, while low-stakes weight-1 criteria passed at 80-90%. 56 of 108 critical (weight-5) criteria (52%) were satisfied by no model. Three LLM autoraters reproduced expert met/not-met labels on 92.8-94.7% of 552 graded criteria. We position this as a methods-and-preliminary-findings contribution: the five tasks demonstrate a scalable, defensible pipeline ready to develop into a large-scale benchmark.
Findings show that clinical LLM explainability has shifted toward fluent generative rationales, but evidence that such explanations reflect model reasoning remains limited, and three regulatory priorities are highlighted: prioritizing explanations that enable independent verification or logic auditing over plausibility...
Claude Fable 5, Anthropic's most capable publicly available model, is evaluated across eight biomedical benchmarks, four text and four multimodal, using deterministic scoring against fixed answer keys throughout.
D. Okonkwo, Magnus D. Hodgson, T. David et al.· arXiv.org· 0 citations
Background/Objectives: Large language models (LLMs) show promise for clinical decision support, yet their accuracy in interpreting specialized medical guidelines remains uncertain. Retrieval-augmented generation (RAG) may enhance performance by grounding responses in authoritative knowledge bases. This study aimed to c...
Andreas Vollmer, Lara K. Schorn, Felix Schrader et al.· Diagnostics· 0 citations
Large Language Models (LLMs) achieve strong results on many medical benchmarks, but their clinical reasoning remains difficult to evaluate reliably. A central risk is an evaluation illusion: fluent and well-structured explanations can appear clinically convincing even when the final diagnosis is incorrect. We introduce...
Abin Roy, Afthab Salam Kanniyan, Jawadh Abdul Kabeer et al.· arXiv.org· 0 citations
Stakeholder role-prompting fundamentally alters clinical decisions and ethical value frameworks of frontier LLMs, with the insurer role producing systematic denial of physician-endorsed, patient-preferred treatments.
C. Dave, A. Diviero, T. Dassanayake et al.· medRxiv· 0 citations
A dual-view approach that connects clinical practice with computational methods is presented, establishing a five-level competency scheme following Miller’s Pyramid and linking deductive, inductive, and abductive reasoning patterns to common medical goals and tasks.