TL;DR
Overexpression of circ_0070190 remarkably suppressed the proliferation, migration, and invasion of CC cells, and the circ_0070190/miR-587 regulatory axis may offer a potential novel target for the targeted therapy of CC.
BACKGROUND Circular RNA (circRNA) has been recognized as critical regulator in cancer progression. However, the mechanisms of circ_0081069 in breast cancer (BC) remain understood. The study was designed to elucidate the pathological significance and mechanism of circ_0081069 in BC. MATERIAL AND METHODS The expression...
As an oncogenic circRNA, hsa_circ_0001839 is critically implicated in gastric cancer progression and unfavorable patient outcomes, underscoring its dual application as a promising prognostic biomarker and a potential therapeutic intervention target.
In vivo, knockdown of circARID1A inhibits tumor growth in subcutaneous xenograft models and promotes GC cell proliferation, migration, and invasion by regulating the miR-147a/SNAI2 axis.
Background: Circular RNAs (circRNAs) are recognized as critical regulators of gastric cancer (GC) progression. Nevertheless, the biological function of circ_0088302 in gastric cancer and its epitranscriptomic regulatory mechanism remain unclear. Methods: The expression of circ_0088302 was analyzed based on plasma circR...
MicroRNA-2110 has been implicated in cancer, but its expression and function in gastric cancer (GC) remain understudied. This study aims to explore the role of miR-2110 in GC and its regulation of IGF1R. RT-qPCR was used to measure miR-2110, IGF1R expression in 138 paired GC and adjacent normal tissues. Ex...
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