[Expression and immunogenicity of porcine deltacoronavirus S-trimer protein].

Generation and epitope mapping of monoclonal antibodies targeting the avian reovirus S1133 σC protein

Avian reovirus (ARV) causes of multisystemic, immunosuppressive infectious diseases in poultry. Among them, the σC protein, a structural component of the outer capsid encoded by the S1 genome segment, plays a crucial role in viral attachment and cellular entry. In this study, we expressed the σC protein derived from th...

Engineering a dimeric porcine deltacoronavirus S-RBD subunit vaccine for enhanced immunogenicity and neutralizing antibody responses

Porcine deltacoronavirus (PDCoV) is an emerging swine enteric coronavirus that has caused global epidemics and substantial economic losses, posing a potential risk of cross-species transmission, including to humans. However, commercial vaccines are currently scarce. The receptor binding domain (RBD) of the spike (S) pr...

Research Paper Expression and Purification of LigA Antigen, a Surface Lipoprotein in the Pathogenic Leptospira interrogans

Secretory expression of tetrameric neuraminidase enhanced by signal peptide optimization elicits robust immunity against influenza infection in mice.

An optimized signal peptide, opt-sp, is developed by introducing valine and asparagine residues at the N-terminus of the Gaussia luciferase signal peptide (Gluc-sp) and incorporating a measles virus phosphoprotein-derived tetramerization domain to identify a promising signal peptide candidate for improving recombinant...

[Preparation and characterization of porcine IL-2 monoclonal antibodies].

Diagnostic performance of a baculovirus-expressed Tc-CPC-polyhedrin fusion protein in chronic Chagas disease.

Diagnosis of chronic Chagas disease relies on serological assays and usually requires concordant results from tests based on different antigenic preparations because assay performance may be affected by parasite diversity and cross-reactivity. The development of well-characterized recombinant antigens therefore remains...