The yak (Bos grunniens) is a crucial species adapted to the extreme high-altitude environment of the Tibetan Plateau. However, a systematic understanding of how gut metabolic homeostasis contributes to this adaptation, particularly across altitudinal gradients and in comparison with sympatric species, remains limited....
Dan Li, Jian Zhang, Li-Ping Zhang et al.· Veterinary Sciences· 0 citations
It is demonstrated that low-pH pretreatment of the porcine stomach induces specific conformational changes in the PDCoV S protein, thereby maximizing the exposure of its receptor-binding domain, enhancing its binding to the host receptor, and promoting infection of intestinal epithelial cells.
Rui-Ming Yu, Li-Ping Zhang, Peng-Lai Zhou et al.· Journal of Virology· 0 citations
The PDCoV S-trimer protein expressed in this study has good immunogenicity, providing biomaterials for the subsequent study of PDCoV S protein structure, the screening of specific monoclonal antibodies, and the development of subunit vaccines.
Rui-Ming Yu, Li-Ping Zhang, Zhong-Wang Zhang et al.· Sheng wu gong cheng xue bao...· 0 citations
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