Phytoextract-loaded bioinspired PLGA nanofibrous scaffold promotes diabetic wound healing via anti-inflammatory and antioxidant effects in in vitro and in vivo experimental models
These findings demonstrate VN+JM-loaded nanofibers could be taken as a promising regenerative scaffold for diabetic wounds by mitigating oxidative stress and inflammation.
It is demonstrated that green-synthesized MSN-enhanced herbal nanofibers represent a safe and promising platform for sustained drug delivery and advanced wound-healing applications.
Hebah Ayash, Gülşah Esen, E. Sabuncu et al.· Molecules· 0 citations
A novel multifunctional wound dressing by integrating Petroselinum crispum (parsley, PS) extract and zinc ascorbate-based metal-organic frameworks (MOFs) into a polyvinyl alcohol (PVA) nanofibrous matrix that combines biodegradability, biocompatibility, and enhanced bioactivity for wound healing is reported.
Shimaa Husien, Rana R. Haikal, Eman A. Khalil et al.· Journal of Biological Engine...· 0 citations
The developed system with remarkable wound healing potential was displayed, displaying chemical stability, improved aqueous solubility and wound area reduction in the present study.
Kirandeep Kaur, A. Monga, Anshula Mehra et al.· Journal of Microencapsulatio...· 0 citations
The Rg3@HMS-Gel hydrogel effectively integrates therapeutic delivery, tissue regeneration, and microbiota modulation, offering a promising strategy for advanced wound management.
A novel multifunctional wound dressing based on a composite of tannic acid-silver self-assembled nanoparticles (TA-AgNPs) and electrospun nanofiber membranes (NFMs) that combines excellent biocompatibility with mechanical properties demonstrates promising applications in chronic wound treatment.
Existing wound dressings are inherently limited by their insufficient antioxidant capacity, which fails to modulate the excessive oxidative stress at the injury site, alongside the well-recognized risks of bacterial infection and the escalating threat of antibiotic resistance that disrupts microbial homeostasis. To c...