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Author

Satyam Sharma

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Sep 2026

Design, Discovery, Synthesis, Molecular Docking, MD Simulation, and In Vitro Biological Evaluation of Thiazolidinedione-Clubbed Benzimidazole Hybrids as Potential Anticancer Agents.

INTRODUCTION/OBJECTIVE Breast cancer is a major global health issue. A new series of thiazolidinedione-benzimidazole hybrid derivatives (TBZ1-15) was developed and tested for anticancer properties against the MCF-7 breast cancer cell line using the MTT assay. Among these compounds, TBZ-13 showed the greatest cytotoxici...

P. Dubey, D. Pathak, Archana Sharma et al. · 0 citations
Sep 2026

Integrated bioinformatics and experimental validation reveal Luteolin targets the PI3K/AKT/NRF2 Axis in diabetic wound healing.

BACKGROUND Diabetic wound healing represents a critical global health challenge, with India harbouring over 77 million diabetic adults and diabetic foot ulcer prevalence ranging from 4.5 to 15%. The complex pathophysiology involves chronic inflammation, impaired angiogenesis, and excessive oxidative stress that fundame...

Shricharan Pandey, Mrinmoy Chakraborty, Krishna Priya Jha et al. · 0 citations
Sep 2026

Phytoextract-loaded bioinspired PLGA nanofibrous scaffold promotes diabetic wound healing via anti-inflammatory and antioxidant effects in in vitro and in vivo experimental models

These findings demonstrate VN+JM-loaded nanofibers could be taken as a promising regenerative scaffold for diabetic wounds by mitigating oxidative stress and inflammation.

Garima Sahu, Mukul Maurya, Satyam Sharma et al. · 0 citations

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