Cross-stress memory in plants: mobile RNAs, extracellular vesicles, and local-to-systemic signal integration

Causal Validation of Mobile RNA and Extracellular Vesicle Signals in Plants: Experimental Frameworks for Sequential Stress Acclimation.

Long-distance molecular transport contributes to coordination between locally stressed tissues and distal organs, but assigning causal systemic-signaling functions to mobile RNAs and extracellular vesicle (EV)-associated molecules remains experimentally challenging. This review critically evaluates the evidence require...

Plant EV small RNAs as programmable cross-kingdom signals: Mechanisms, evidence standards, and crop protection.

Plant extracellular vesicles (EVs) have emerged as candidate carriers of small RNAs that connect intracellular RNA regulation with apoplastic defense, intercellular signaling, and cross-kingdom communication. The field is advancing rapidly, yet its central mechanistic claims remain unevenly resolved because RNA detecti...

The miRNA-ROS interactome: Orchestrating plant resilience to environmental fluxes.

This review examines how miRNAs compartment-specific regulate ROS metabolism in the apoplast, mitochondria, and chloroplasts, and delineates the multi-layered control of miRNA biogenesis by ROS, encompassing redox-sensitive transcription factors, epigenetic modifications, and post-translational modifications.

Rapid Whole-Plant Signalling Under Compound Environmental Stresses: Systemic Integration, Stomatal Coordination and Stress Memory.

This review develops a mechanistic framework for rapid whole-plant stress signalling under compound environmental stresses and outlines an experimental pipeline combining live biosensors, electrophysiology, vascular imaging, spatial omics, perturbation genetics and crop phenotyping.

m6A-m5C epitranscriptomic regulation of plant stress memory and development: mechanisms and physiological effects

Epigenetic regulation and ROS signaling in plant stress adaptation: an integrated framework

This review examines the bidirectional interactions between epigenetic mechanisms and ROS homeostasis in plant stress adaptation, with a particular emphasis on drought resistance, and proposes that these interactions take the form of dynamic regulatory networks rather than one-way pathways.