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Open access Aug 2026

Adversity and brainAGE associations with age of first cannabis use in the Adolescent Brain Cognitive Development (ABCD) Study

Investigation of magnetic resonance imaging-derived neurodevelopmental cortical brain Age Gap Estimate and adverse life events as risk factors of early cannabis initiation suggest that while cortical brainAGE may be somewhat increase vulnerability to adolescent cannabis use in females, its contributions are modest at b...

K. Thiessen, Y. Yu, L. Schmid et al. · 0 citations
Open access Sep 2026

Hippocampal volume and persistent distressing psychotic-like experiences across early adolescence: the moderating role of physical activity

Background. Persistent distressing psychotic-like experiences (PLEs) in youth are associated with cognitive, functional, and psychiatric impairments. Reduced hippocampal volume (HV) is a nonspecific neurodevelopmental risk marker across psychiatric disorders. While physical activity is associated with better mental hea...

B. Ku, E. Arrant, Katherine S. F. Damme et al. · 0 citations
Open access Sep 2026

EEG Functional Connectivity Reveals Accelerated Brain Aging in Young Adults with Cognitive Deficits and Mental Health Conditions

The discrepancy between chronological age and predicted brain age, derived from neuroimaging data, serves as a biomarker for neurological health. However, the exact electroencephalography (EEG) mechanisms contributing to the variation of brain age are yet to be understood. This paper comprehensively investigated the re...

C. Phang, Guo-Dong Miao, Lan-Tu Cai et al. · 0 citations
Open access Sep 2026

Brain deviation scores derived from normative modelling identify dimensions of psychopathology in children and adolescents

Psychiatric diagnoses lack neurobiological grounding, and brain-based abnormalities correspond poorly to established diagnostic categories. While multivariate algorithms extract transdiagnostic dimensions from brain–behavior covariation, most studies rely on conventional structural morphometric measures such as cortica...

Zheng Li, B. Ren, Hao Wu et al. · 0 citations
Open access Aug 2026

Examination of poverty trajectories and brain volume as predictors of adolescent depression.

Adolescence is a sensitive period during which socioeconomic conditions can shape brain development and mental health. To further clarify such pathways, the present study examined how trajectories of different poverty indices across adolescence relate to brain structure and depressive symptomatology. In a sample of 206...

B. Hayes, Yiming Qian, Myles N. Arrington et al. · 0 citations

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