A Compact Stance-Indexed Anterior-Posterior COP Representation for Parkinson's Disease Classification from Plantar VGRF

Abstract

Parkinson's disease alters gait and bilateral coordination, but machine-learning performance also depends on how continuous gait signals are represented. This study investigates whether preserving anterior-posterior center-of-pressure (AP-COP) information at fixed locations across normalized stance provides a compact and informative representation of plantar-force gait signals. Bilateral vertical ground reaction force recordings from 165 participants in the Gait in Parkinson's Disease Database were evaluated using repeated fully nested participant-level cross-validation. We propose AP-COP10, comprising AP-COP position and bilateral asymmetry across five stance windows. AP-COP10 achieved an AUC of 0.894 and outperformed three harmonized literature-derived COP representations under the same evaluation pipeline. The complementary 25 non-AP-COP descriptors alone achieved an AUC of 0.856, while the complete 35-feature representation achieved 0.908. Removing AP-COP10 from the complete representation produced a statistically supported loss in discrimination, whereas adding the complementary descriptors to AP-COP10 yielded only a small, unsupported improvement. Feature competition indicated that the most informative stance-indexed descriptors were concentrated in early and early-mid stance, while source-study holdout and sensor-perturbation analyses supported the robustness of the representation. These findings indicate that stance-indexed AP-COP retains discriminative information that is not readily recovered by broader engineered gait descriptors, supporting compact and interpretable representations for machine-learning analysis of pathological gait.