Inferring 3D cellular properties from 2D microscopy is difficult when a reference instrument reports only population statistics rather than labels for individual cells. Here we develop a population-supervised framework that maps single 2D red-cell images to latent biophysical quantities and aggregates them to mean corpuscular volume, red-cell distribution width and mean corpuscular haemoglobin. The model combines shared local inference, a biophysically structured decoder for volume and haemoglobin, learned instance weighting and device-specific calibration. We formalise conditions under which aggregate observations identify restricted instance predictors, show why population agreement does not by itself identify single-cell properties or 3D geometry, and derive the dispersion penalty induced by subset mean matching. The development dataset comprises 390 specimens and 1,105 acquisitions across six devices, with reported Pearson correlations of 0.86--0.98 against a Sysmex analyser. The framework provides a testable route from 2D images and population supervision to 3D cellular biophysics without claiming explicit 3D reconstruction.
GAOKAO-Bench is introduced, an intuitive benchmark that employs questions from the Chinese GAOKAO examination as test samples, including both subjective and objective questions that contribute a robust evaluation benchmark for future large language models and offers valuable insights into the advantages and limitations...
Xiaotian Zhang, Chun-yan Li, Yi Zong et al.· arXiv.org· 216 citations· ⚡17
This work proposes a HALO that directly maximizes the utility of generations instead of maximizing the log-likelihood of preferences, and suggests that the best loss depends on the inductive biases most appropriate for a given setting, an oft-overlooked consideration.
This work investigates the possibilities of using LLMs in a resume screening setting via a document retrieval framework that simulates job candidate selection and finds that the MTEs are biased, significantly favoring White-associated names in 85% of cases and female-associated names in only 11.1% of cases.
This work shows that orders of magnitude enhancement in performance could be obtained by a combination of hardware improvements and tight quantum-HPC integration and introduces high-performance architectures for quantum-probabilistic computing with custom-designed accelerators to tackle today's industry-scale classical...
Masoud Mohseni, Artur Scherer, K. Johnson et al.· arXiv.org· 121 citations· ⚡9
This paper presents a comprehensive overview of the Ultralytics YOLO family, emphasizing architectural evolution, benchmarking, deployment, and emerging directions from YOLOv5 through YOLO27, and examines detection, segmentation, depth, classification, pose, oriented detection, tracking, export, quantization, and deplo...
A novel threat is unveiled in which attackers steer the RAG system's response by injecting malicious passages into its knowledge base, enabling the attacker to steer the response without altering the user input or modifying the RAG weights.
Jiaqi Xue, Meng Zheng, Yebowen Hu et al.· arXiv.org· 109 citations· ⚡8
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MIT News · Artificial Intelligence· news.mit.eduOct 13, 2026
Machine-learning networks can learn without detailed instructions from a designer. Those that do may offer insight into how the brain reorganizes itself during learning.
With $2.1 million funding from Google.org, the open-source Public Transit Intelligence Hub will unify public transit monitoring, operations, and passenger communication.
