It is shown that people who are diagnosed with cancer after microbiome sampling have microbiome alterations like those found in diagnosed cancer cases, albeit to a lower degree, across the four populations studied, indicating that the microbiome may evolve towards the one found in cancer well before cancer is diagnosed.
Cancer remains a leading cause of morbidity and mortality worldwide, and the incidence of new cancer cases is rising. While established lifestyle factors such as smoking, obesity, and diet contribute to cancer risk, the gut microbiome has emerged as a hallmark of cancer. However, the role of the gut microbiome in cance...
E. Oosterhout, R. S. Leijdesdorff, O. Kambur et al.· medRxiv· 0 citations
The gut microbiome has emerged as a key contributor to cancer biology. Prior studies have focused on individual cancers and often overlook comorbidities, obscuring whether reported associations are specific to a cancer type. Here, we present findings from a real-world mixed-cancer cohort (Mayo Clinic Cancer Microbiome)...
Lu Yang, Vaidhvi Singh, Brent J. Gawey et al.· Cell· 0 citations
Cancer is one of the leading causes of death worldwide, and increasing evidence suggests that bacteria and the human microbiome may contribute to its development. The oral microbiome is one of the most diverse microbial communities in the body and may influence both local and systemic diseases. This review summarizes c...
Jakub Rudzki, Zuzanna Kata, Joanna Brzoza et al.· Quality in Sport· 0 citations
The gut microbiome has been linked to cancer in many cross-sectional studies. These studies compared individuals with and without cancer, but they do not establish causation. Prospective cohort studies, with faecal samples collected before a cancer diagnosis, will be instrumental in assessing the role of the gut microb...
E. Vogtmann, Caroline Y. Um, S. Zouiouich et al.· The Lancet Microbe· 0 citations
BCa and inherited genetic susceptibility jointly contribute to increased risk of multiple common diseases, supporting the integration of genetic risk stratification into survivorship care.
Annabelle Ashworth, Zhu-Qing Shi, Huy Tran et al.· JNCI Cancer Spectrum· 0 citations
CRC is the third most prevalent malignancy worldwide and the second leading cause of cancer-related mortality. According to GLOBOCAN 2022 estimates, approximately 1.93 million new CRC cases and 900,000 CRC-related deaths occur annually worldwide. Incidence rates continue to rise in developing countries, driven by the w...
Jun-Hong Liu, Zhong-Hua Qi· Frontiers in Immunology· 0 citations
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