Skip to content
Log in
Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Evaluation of phytochemical-mediated inhibition of the efflux pump in Pseudomonas aeruginosa PAO1

Adarsha Sarmah Aanand Kumar Anto Antony Selvaraj N. Rameshkumar R. Rani Aruni Wilson Santhosh Kumar Vinothkannan Ravichandran
Aug 2026 · Molecular Biology Reports · Vol 53 · 0 citations · 43 references
Medicine

TL;DR

Results position Salvianolic acid A and the other phytochemicals evaluated here as promising adjuvant candidates for tackling multidrug-resistant Pseudomonas aeruginosa, and warrant their continued investigation as adjunctive therapeutic options alongside conventional antibiotics.

DOI PubMed Semantic Scholar
View source

Similar papers

Review Sep 2026

PLANT-DERIVED THERAPEUTICS AS A NOVEL STRATEGY TO COMBAT ANTIMICROBIAL RESISTANCE: CURRENT ADVANCES AND FUTURE PERSPECTIVE

Overall, plant-derived therapeutics represent a promising and sustainable avenue for the discovery and development of complementary antimicrobial strategies to address the growing global burden of AMR.

Deeksha Rathor, Pushpendra Kumar, Km. Neha et al. · 0 citations
Sep 2026

Phytochemical Profiling and Antibiofilm Efficacy of Myrtus communis Extract Against Multidrug-Resistant Pathogens: A Sustainable Biotherapeutic Approach Aligned with Circular Economy Principles

It is demonstrated that methanolic leaf extract of Myrtus communis possesses considerable antibacterial and antibiofilm activities against clinically relevant MDR bacteria, supporting its potential as a natural source for developing alternative antimicrobial strategies.

Methaq Abbas · 0 citations
Open access Aug 2026

Selected Essential Oils Modulate Ethidium Bromide Accumulation and Exhibit Antibacterial Activity Against Multidrug-Resistant Escherichia coli and Klebsiella pneumoniae

The increasing prevalence of multidrug-resistant (MDR) Gram-negative bacteria has stimulated the search for plant-derived antimicrobials with alternative modes of action. This study investigated whether chemically distinct essential oils (EOs) differ in their antibacterial effects and their ability to modulate bacteria...

E. Ormai, Nikoletta Szemerédi, B. Kocsis et al. · 0 citations
Open access Sep 2026

Aqueous extract of Nasturtium officinale: a potential therapeutic approach to be explored in the fight against multidrug-resistant Pseudomonas aeruginosa

The aqueous extract of N. officinale demonstrated promising antimicrobial activity against planktonic strains and biofilms of multidrug-resistant P. aeruginosa, and in cytotoxicity assays, the 50 mg/mL concentration proved to be biocompatible, maintaining keratinocyte viability above 90%.

Chen-Yu Li, Chen Liu · 0 citations
Open access Oct 2026

Luteolin potentiates antibiotic activity against multidrug-resistant Pseudomonas aeruginosa and modulates efflux-associated resistance and biofilm-associated phenotypes

Multidrug-resistant Pseudomonas aeruginosa is a WHO critical-priority pathogen whose recalcitrance is driven largely by efflux pump overexpression and biofilm formation, two mechanisms rarely addressed by a single agent. Here we evaluated whether luteolin, a plant-derived flavone, could potentiate conventional an...

Wei He, Kai-Chong Jiang, Tian-Hao Wang et al. · 0 citations

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.