Antimicrobial resistance (AMR) remains a critical global health challenge, with the RND‐type MexAB–OprM efflux system of
Pseudomonas aeruginosa
playing a central role in intrinsic multidrug resistance (MDR) through the active extrusion of diverse antibiotics. In this study, we screened natural product libraries t...
The rise of multidrug‐resistant (MDR) bacteria poses a serious global health threat.
Pseudomonas aeruginosa
employs quorum sensing (QS) to regulate virulence, making QS inhibition a promising anti‐virulence strategy. Here, 4,687 plant‐derived natural compounds were computationally screened against PqsR, a key tra...
Aziz Mandsaurwala, Renitta Jobby, Vinothkannan Ravichandran· ChemistrySelect· 0 citations
Results position Salvianolic acid A and the other phytochemicals evaluated here as promising adjuvant candidates for tackling multidrug-resistant Pseudomonas aeruginosa, and warrant their continued investigation as adjunctive therapeutic options alongside conventional antibiotics.