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Plasma metabolomic signatures of heterogeneous multimorbidity trajectories in ageing: a population-based cohort study.

Ryota Toki Chisato Iba Yûki Omoto Minako Matsumoto Miho Iida Shun Edagawa S. Harada A. Hirata Naoko Miyagawa Atsuko Miyake A. Hirayama Masahiro Sugimoto Asako Sato Kaori Amano T. Soga K. Arakawa T. Takebayashi
Jul 2026 · GeroScience · 0 citations · 23 references
Medicine

TL;DR

Findings implicate amino acid metabolism, redox balance, and microbiome-host interactions as candidate biological pathways underlying heterogeneous patterns of age-related disease accumulation, and warrant replication in independent cohorts.

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