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Author

A. Hirata

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Open access Sep 2026

Estimated small dense low-density lipoprotein cholesterol in predicting atherosclerotic cardiovascular disease: Longitudinal evidence from over 1 million Japanese adults.

BACKGROUND Small dense low-density lipoprotein cholesterol (sdLDL-C) is an atherogenic LDL-C subfraction associated with atherosclerotic cardiovascular disease (ASCVD). Although sdLDL-C integration into major routine risk assessments remains limited, partly because of requiring additional lipid tests, a more implementa...

Koki Ono, A. Hirata, T. Okamura · 0 citations
Jul 2026

Plasma metabolomic signatures of heterogeneous multimorbidity trajectories in ageing: a population-based cohort study.

Findings implicate amino acid metabolism, redox balance, and microbiome-host interactions as candidate biological pathways underlying heterogeneous patterns of age-related disease accumulation, and warrant replication in independent cohorts.

Ryota Toki, Chisato Iba, Yûki Omoto et al. · 0 citations

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