Category
2,046 papers
This work reviews the computational and experimental approaches that disentangle folding and function at scale, revealing a dark energy component and providing new insights into how biological information flows from sequence to structure to function and back to sequence.
The current work highlighted the potential of polymer-based excipient systems for developing high-concentration injectable suspensions of proteins and their combinations on the viscosity, injectability, and stability.
Endothelial DANCR deficiency promotes atherosclerotic plaque instability through activation of the RPL22/p53 pathway, suggesting DANCR as a potential protective factor and therapeutic target in atherosclerosis.
This research investigates the potential role of quantum entanglement in biological information processing. We explore the feasibility of simulating quantum effects within biological molecules and examining the influence of entanglement on fundamental processes such as DNA sequence recognition and protein folding. The...
Reach audiences
Advertise in front of researchers, engineers, and readers.
Description:1. Core Scientific ThesisThis repository serves as a comprehensive scientific reference and educational framework for substrate-native, integer-only computation. It demonstrates that the current reliance on IEEE-754 floating-point arithmetic introduces unnecessary thermodynamic overhead, non-determinism, an...
Predicting protein three-dimensional structures from their amino acid sequences remains a grand challenge in computational biology. Traditional methods have struggled to accurately capture the complex, long-range interactions that govern protein folding. This work proposes a novel approach utilizing Graph Neural Networ...
This record contains the code-associated data and figures for "Tensor-based Approximation of Molecular Kinetics: Generator Learning, Reaction Coordinates and Incremental Updating". It provides the precomputed data, results, and figures behind four case studies: a 3D Lemon-Slice toy system, and molecular dynamics trajec...
Description:1. Core Scientific ThesisThis repository serves as a comprehensive scientific reference and educational framework for substrate-native, integer-only computation. It demonstrates that the current reliance on IEEE-754 floating-point arithmetic introduces unnecessary thermodynamic overhead, non-determinism, an...
A fundamental theoretical framework for the development of specialized foods that possess safe swallowing and nutritional attributes is offered and the polarity of the tryptophan residue microenvironment alters and impeding the further folding of unfolded protein structures during heat-induced gelation is examined.
The XGBoost model developed in this study achieved a relatively high AUC of 0.901, indicating that the model’s ability to confirm prolonged PACU stay remains somewhat insufficient, and can be used as an auxiliary screening tool in clinical rather than a definitive diagnostic tool.
It is demonstrated that the oral microbiome differs between patients with AAA and those with advanced atherosclerotic disease and support further investigation of oral microbial alterations and their relationship to vascular pathologies.
Understanding plant responses to co-occurring metal contamination is essential for evaluating their phytoremediation potential, yet the physiological and molecular responses of Cyperus esculentus (CES) to combined Cu, Zn, and Cd exposure remain poorly understood. Here, CES plants were exposed to combined Cu, Zn, and Cd...
Proof of concept for watermarking AI-generated proteins while preserving biological function.
A new machine-learning framework aims to improve the success rate of computational protein design while moving away from results that reproduce sequences found in nature.
Scientists are using AlphaFold to strengthen a photosynthesis enzyme for resilient, heat-tolerant crops.
Explore how AlphaFold has accelerated science and fueled a global wave of biological discovery.
AlphaFold has revealed the structure of a key protein behind heart disease
We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.
