Hepatitis is a leading cause of morbidity and mortality. It is a significant global public health challenge, affecting more than 300 million people worldwide. Achieving a hepatitis free future requires an integrated approach that combines medical innovation, public health initiatives, and equitable healthcare delivery....
Mugdivari Sangeetha, G. Akshitha, T .Satvika, V. Srinidhi, V. Uma MaheswarRao· Zenodo (CERN European Organi...· 0 citations
This dataset contains the digitized treatments in Plazi based on the original journal article Moya, Gabriela, Yan, Zheng-Fei, Chu, Dong-Hun, Won, KyungHwa, Yang, Jung-Eun, Wang, Qi-Jun, Kook, Moo-Chang, Yi, Tae-Hoo (2018): Deinococcus hibisci sp. nov., isolated from rhizosphere of Hibiscus syriacus L. (mugunghwa flower...
Gabriela Moya, Zheng‐Fei Yan, Dong-Hun Chu et al.· Global Biodiversity Informat...· 0 citations
Efficient multiplex genome editing is essential for improving complex traits in livestock that are governed by multiple genes. However, achieving high‐efficiency simultaneous editing at multiple loci remains challenging for cytosine base editors (CBEs), largely due to variable editing efficiencies and limited deamina...
Shao-Shuai Wang, Yu Wang, Deng-Feng Bi et al.· Animal Research and One Heal...· 0 citations
An in-depth literature review of the current approaches to informed consent for somatic gene editing and gene therapy and identify potential areas for improvement, specifically in relation to SCD in sSA is conducted.
Patrick Ohiani Moru, O. Nnodu, V. Nembaware et al.· BMC Medical Ethics· 0 citations
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Tomato (Solanum lycopersicum) faces increasing pressure from both biotic threats, including bacterial, fungal, and viral pathogens, and abiotic stresses such as drought, salinity, heat, and cold, all of which substantially reduce productivity under changing climatic conditions. CRISPR/Cas-based genome editing has emerg...
Xi-Jun Sun, Ke Wang, Ming-Ming Gao et al.· Crop Breeding, Genetics and...· 0 citations
Genetic neuromuscular disorders (NMDs) that predominantly affect muscle tissue are individually rare but cumulatively are responsible for significant clinical and economic burdens on patients and healthcare systems. Few effective, targeted therapies exist outside of the Duchenne muscular dystrophy (DMD) landscape, high...
Purpose: The short lifespan of primary normal choroidal melanocytes (NCMs) in vitro represents a major barrier to mechanistic, functional, and translational studies of choroid biology and uveal melanoma (UM). This study aimed to establish and characterize immortalized human NCM lines that retain melanocytic function, m...
Aurélie Fuentes-Rodriguez, Andrew Mitchell, Vincent Gelinas et al.· Investigative Ophthalmology...· 0 citations
What's Changed ZFIN-10286: soften diff highlight + add gene-symbol columns to report by @rtaylorzfin in https://github.com/ZFIN/zfin/pull/1919 ZFIN-10373: Solr backup/restore: per-instance backup, restore from shared zfindb by @rtaylorzfin in https://github.com/ZFIN/zfin/pull/1929 ZFIN-10388: Fix manually named STRs ig...
Christian Pich, Ryan Taylor, zfinryanm et al.· Zenodo (CERN European Organi...· 0 citations
This review discusses this emerging field and its transformative potential for translational neuropharmacology, focusing on therapies for neurodevelopmental and neurodegenerative disorders.
The results showed that AAV2-OCRL demonstrated the highest transduction efficiency in patient iPSC-derived trabecular meshwork models (iHTM) among the three AAV-OCRL vectors evaluated, establishing it as a promising delivery vector.
Si-Yu Chen, Zhi-Quan Liu, Wen-Min Wang et al.· Advancement of science· 0 citations
This study provides the first CRISPR-oriented functional characterisation and sgRNA validation of the M. vitrata Vg gene, together with structural characterisation of VgR and Vg-VgR interaction analysis, providing preliminary molecular resources for future CRISPR/Cas9 studies and supporting future embryo microinjection...
C. Pradeep, Parvathy Madhusoodanan Sujatha, S. Nagesha et al.· Bulletin of entomological re...· 0 citations
ABSTRACT Alfalfa (Medicago sativa) is the most widely cultivated forage crop worldwide, owing to its high protein content, balanced amino acid profile, and abundance of vitamins and minerals. However, weed infestation severely threatens alfalfa yield and quality. The lack of herbicide‑resistant cultivars, combined with...
Exploring how generative AI could make machine vision more accessible to businesses. The post GenEye in a Box: Making Machine Vision Something You Can Just Ask For appeared first on GPT-Lab.