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gene editing

1,411 papers

#gene editing Open access Sep 2026

THE BLUEPRINT FOR A HEPATITIS- FREE FUTURE: INNOVATION IN ACTION

Hepatitis is a leading cause of morbidity and mortality. It is a significant global public health challenge, affecting more than 300 million people worldwide. Achieving a hepatitis free future requires an integrated approach that combines medical innovation, public health initiatives, and equitable healthcare delivery....

Mugdivari Sangeetha, G. Akshitha, T .Satvika, V. Srinidhi, V. Uma MaheswarRao · 0 citations
#gene editing Dataset Open access Sep 2026

Deinococcus hibisci sp. nov., isolated from rhizosphere of Hibiscus syriacus L. (mugunghwa flower)

This dataset contains the digitized treatments in Plazi based on the original journal article Moya, Gabriela, Yan, Zheng-Fei, Chu, Dong-Hun, Won, KyungHwa, Yang, Jung-Eun, Wang, Qi-Jun, Kook, Moo-Chang, Yi, Tae-Hoo (2018): Deinococcus hibisci sp. nov., isolated from rhizosphere of Hibiscus syriacus L. (mugunghwa flower...

Gabriela Moya, Zheng‐Fei Yan, Dong-Hun Chu et al. · 0 citations
#gene editing Open access Sep 2026

MiniSdd7‐Derived Cytosine Base Editor Promotes Efficient Multiplex Gene Knockout in Porcine Primary Fibroblasts

Efficient multiplex genome editing is essential for improving complex traits in livestock that are governed by multiple genes. However, achieving high‐efficiency simultaneous editing at multiple loci remains challenging for cytosine base editors (CBEs), largely due to variable editing efficiencies and limited deamina...

Shao-Shuai Wang, Yu Wang, Deng-Feng Bi et al. · 0 citations
#gene editing Review Open access Sep 2026

Informed consent for somatic gene editing for sickle cell disease in sub-Saharan Africa: a scoping review

An in-depth literature review of the current approaches to informed consent for somatic gene editing and gene therapy and identify potential areas for improvement, specifically in relation to SCD in sSA is conducted.

Patrick Ohiani Moru, O. Nnodu, V. Nembaware et al. · 0 citations
#gene editing Review Open access Sep 2026

Genome Editing for Biotic and Abiotic Stress Resistance in Tomato: Advances Enabled by CRISPR/Cas Systems

Tomato (Solanum lycopersicum) faces increasing pressure from both biotic threats, including bacterial, fungal, and viral pathogens, and abiotic stresses such as drought, salinity, heat, and cold, all of which substantially reduce productivity under changing climatic conditions. CRISPR/Cas-based genome editing has emerg...

Xi-Jun Sun, Ke Wang, Ming-Ming Gao et al. · 0 citations
#gene editing Open access Sep 2026

Variant-agnostic modulation of gene expression to identify novel treatments for genetic neuromuscular disorders

Genetic neuromuscular disorders (NMDs) that predominantly affect muscle tissue are individually rare but cumulatively are responsible for significant clinical and economic burdens on patients and healthcare systems. Few effective, targeted therapies exist outside of the Duchenne muscular dystrophy (DMD) landscape, high...

Anthea Lee · 0 citations
#gene editing Open access Sep 2026

Establishment of Stable Immortalized Human Choroidal Melanocytes for Ocular Research

Purpose: The short lifespan of primary normal choroidal melanocytes (NCMs) in vitro represents a major barrier to mechanistic, functional, and translational studies of choroid biology and uveal melanoma (UM). This study aimed to establish and characterize immortalized human NCM lines that retain melanocytic function, m...

Aurélie Fuentes-Rodriguez, Andrew Mitchell, Vincent Gelinas et al. · 0 citations
#gene editing Open access Sep 2026

ZFIN/zfin: Release 1184

What's Changed ZFIN-10286: soften diff highlight + add gene-symbol columns to report by @rtaylorzfin in https://github.com/ZFIN/zfin/pull/1919 ZFIN-10373: Solr backup/restore: per-instance backup, restore from shared zfindb by @rtaylorzfin in https://github.com/ZFIN/zfin/pull/1929 ZFIN-10388: Fix manually named STRs ig...

Christian Pich, Ryan Taylor, zfinryanm et al. · 0 citations
#gene editing Review Sep 2026

Opto-CRISPR technologies in translational neuropharmacology.

This review discusses this emerging field and its transformative potential for translational neuropharmacology, focusing on therapies for neurodevelopmental and neurodegenerative disorders.

Cia-Hin Lau, Qi-Yuan Xia, Qing-Le Liang et al. · 0 citations
#gene editing Open access Sep 2026

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

The results showed that AAV2-OCRL demonstrated the highest transduction efficiency in patient iPSC-derived trabecular meshwork models (iHTM) among the three AAV-OCRL vectors evaluated, establishing it as a promising delivery vector.

Si-Yu Chen, Zhi-Quan Liu, Wen-Min Wang et al. · 0 citations
#gene editing Sep 2026

Molecular characterization of vitellogenin and its receptor with CRISPR-based sgRNA validation in the legume pod borer, Maruca vitrata (Geyer) (Lepidoptera: Crambidae).

This study provides the first CRISPR-oriented functional characterisation and sgRNA validation of the M. vitrata Vg gene, together with structural characterisation of VgR and Vg-VgR interaction analysis, providing preliminary molecular resources for future CRISPR/Cas9 studies and supporting future embryo microinjection...

C. Pradeep, Parvathy Madhusoodanan Sujatha, S. Nagesha et al. · 0 citations
#gene editing Open access Sep 2026

Generation of Herbicide‐Resistant Alfalfa Germplasm via Prime Editing

ABSTRACT Alfalfa (Medicago sativa) is the most widely cultivated forage crop worldwide, owing to its high protein content, balanced amino acid profile, and abundance of vitamins and minerals. However, weed infestation severely threatens alfalfa yield and quality. The lack of herbicide‑resistant cultivars, combined with...

Shi-Hao Li, Xiu-Zhi Xia, Zheng-Zheng Wei et al. · 0 citations

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Google DeepMind Blog Sep 30, 2026

Introducing SynthID Bio

Proof of concept for watermarking AI-generated proteins while preserving biological function.

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