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1,434 papers
This first-in-human study demonstrated the feasibility of an "off-the-shelf" base-edited CAR T cell approach and informs future multiantigen strategies against AML.
Cell-specific epigenetic editing holds very high therapeutic value for atherosclerosis, cardiomyopathy, and fibrosis, provided that delivery, specificity, and safety challenges are also addressed.
This synthesis provides a framework for translating mechanistic hormonal insights into field-applicable cultivars to ensure global food security and proposes a systems-level roadmap for developing climate-resilient rice cultivars capable of maintaining yield stability across a volatile combinatorial stress landscape.
Results indicate that targeted reactivation of BFL-1 and SQOR increases cell-death susceptibility in liver cancer cells, providing proof-of-concept for locus-specific epigenetic therapy in liver cancer.
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This targeted modification markedly improved rice eating and cooking quality while maintaining the levels of total starch, total protein, and key agronomic traits.
The gene-edited mFD-PEVs reprogram redox homeostasis in NPCs, regulate ferroptosis, and promote intervertebral disc regeneration.
Post-training alignment is often shallow, eroding under fine-tuning. It remains untested as to whether constitutional midtraining interventions can produce durable alignment when cleanly isolated from post-training. We build a 394M-token constitutional corpus from Anthropic's Constitution and apply constitutional midtr...
It is demonstrated that local nucleosome sequence and structure profoundly influence Cas nuclease accessibility and specificity, with HIFIv1 emerging as the top-performing nuclease for nucleosomal targets, while evoSpCas9 excelled in exposed contexts.
Exposure to airborne nickel in the average daily dose, combined with the minor C-allele and CC-genotype of the VEGFA induces changes in indices of cell death and the immune profile in adults in the Far North (declining AnnexinV-FITC+7AAD– levels, growing levels of VEGF and IgE to nickel).
Perceived risks associated with food production are a major concern among European consumers and strongly influence debates on sustainable agricultural practices. In particular, the adoption of precision-bred (gene-edited) crops and the use of alternative pesticide strategies raise questions about consumer acceptance a...
Reducing the incidence and mortality rates of breast cancer requires comprehensive regional scientific approaches, including epidemiological, medico-demographic, hygienic, clinical, and molecular-genetic studies as the basis for integrated information for the elaboration and implementation of early diagnosis and preven...
This narrative review critically evaluates emerging biotechnology- and artificial intelligence (AI)enhanced approaches for hyperlipidemia, emphasizing translational maturity, clinical applicability, and regulatory implications.
GPT-Lab
· gpt-lab.eu
Oct 8, 2026
Exploring how generative AI could make machine vision more accessible to businesses. The post GenEye in a Box: Making Machine Vision Something You Can Just Ask For appeared first on GPT-Lab.
A Blog post by Ai2 on Hugging Face
A Blog post by ServiceNow-AI on Hugging Face
“InstructMesh” can generate designs for everyday objects that are easy to edit and fabricate for both experts and newcomers to 3D modeling.
Proof of concept for watermarking AI-generated proteins while preserving biological function.
Algorithms & Theory
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