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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Zi-Ying Huang

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Open access Aug 2026

Single-cell and bulk transcriptomic profiling of M2-like tumor-associated macrophages reveals a prognostic signature and an inflammation–metabolism crosstalk program in multiple myeloma

Highlights • Seven MM-specific M2-TAM subsets (MM-M2) are absent in normal bone marrow.• MM-M2 subclusters exhibit distinct transcription factor programs via SCENIC.• Enhanced ligand–receptor signaling links MM-M2 to plasma and stromal cells.• An 11-gene RSF-derived MRGs signature stratifies MM patients by survival.• M...

Hui Zhao, Jing Kang, H. Ouyang et al. · 0 citations

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