Open access
Sep 2026
Directing GABAergic neuronal identity from human iPSCs through developmental patterning.
GABAergic interneurons are implicated in numerous neurodevelopmental and neuropsychiatric disorders. Transcription factor (TF)-mediated induction of human pluripotent stem cells (PSCs) rapidly generates GABAergic neurons, yet their regional identity remains poorly defined. Here, we show that the chromatin state of the...
Rui-Qi Hu, Linda L. Boshans, Yi-Ran Tao et al.
· Stem Cell Reports · 0 citations