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Author

Yun-Xiao Qiao

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Review Sep 2026

Castration-resistant prostate cancer as an adaptive tumor ecosystem: coupling tumor evolution with microenvironmental reprogramming

A system-level framework is proposed in which CRPC is viewed as an adaptive tumor ecosystem shaped by evolutionary selection, cellular plasticity, and microenvironmental co-evolution under therapeutic pressure and therapeutic strategies aimed at reprogramming or destabilizing adaptive tumor ecosystems are highlighted.

Si-Liang Wang, Xin-Yi Xu, Ming-Huang Xu et al. · 0 citations

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