Open access
Aug 2026
An On-Demand Nanodisc Platform for Reconstitution of Functional Membrane Proteins into Model and Living Membranes
Nodiscs can serve not only as stabilizing membrane mimetics but also as active delivery vehicles for on-demand membrane protein reconstitution, providing a rapid and broadly applicable platform for interrogating ion channels, GPCRs, and other challenging pharmacological targets in user-defined membrane environments.
Long-Kai Chen, Yun-Shan Wang, Wei-Hsuan Chang et al.
· bioRxiv · 0 citations