A-to-I RNA editing remodeling across CD11b/CD14/CD16-defined synovial monocyte-macrophage cell states
Knee osteoarthritis (OA) is a disabling whole-joint disease involving synovial inflammation and myeloid-cell activation. A-to-I RNA editing can regulate endogenous dsRNA sensing and protein recoding, but its dynamics across synovial monocyte-macrophage cell states remain unclear. We analyzed 12 RNA-seq libraries from s...
Yingming Chu, Boyang Yi, Xinyue Cao et al.
· Human Genomics · 0 citations