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2026

[Hepatocellular carcinoma-derived lactate-mediated histone H3K18 lactylation modifies S100A2 transcription to promote proliferation, migration, invasion and epithelial-mesenchymal transition of hepatocellular carcinoma cells].

HCC-derived lactate enhances H3K18la modification, which activates S100A2 transcription to positively regulate the Wnt/β‑catenin pathway, ultimately promoting the proliferation, migration, invasion and EMT of HCC cells.

Li-Ping Huang, Yu Shao, Wan-Bing Zhou et al. · 0 citations

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