RSE-Bench is introduced, to the authors' knowledge the first benchmark for evaluating skill self-evolution under ordinary, non-adversarial noise, and a method-agnostic framework supporting consistent noise injection and process diagnostics of actual exposure and skill updates is introduced.
Tao Yu, Zhong-Tian Luo, Yu-Chen Long et al.· 0 citations
Diploid genomes carry millions of heterozygous variants in cis-regulatory DNA, yet most genes produce similar RNA output from two parental alleles. How this balance is maintained is unclear. We developed Nanopore-HiChIP, a long-read method that maps high-order enhancer hubs on each haplotype. Over half of these enhance...
Jiang Tan, M. Sentmanat, Yu-Qing Wu et al.· bioRxiv· 0 citations
NextLongIso is presented, a scalable and reproducible Nextflow pipeline that enables coordinated analysis of multiple layers of transcript regulation and facilitates the transition from transcript identification to functional interpretation of transcriptomic variation.