Author

Yi-Jie Ding

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Open access Sep 2026

Structure-based virulence factor classification using a dual-driven graph transformer with a pretrained language model

Abstract Bacterial pathogenicity relies on a multitude of virulence factors (VFs). Identifying these factors is crucial for comprehending the molecular mechanisms driving bacterial pathogenesis and pinpointing potential targets for antivirulence strategies. While the identification of VFs has received extensive attenti...

Pei-Hao Bai, Guang-Hui Li, Nan Jiang et al. · Briefings in Bioinformatics · 0 citations

#graph neural networks Open access Sep 2026

A unified framework for potency-oriented AMP discovery via multi-modal learning and guided sequence synthesis

The generation-screening-validation workflow enables reliable discovery of potent AMPs, and provides a practical strategy for rational peptide design, rapid prediction, and translational applications.

Wen-Yu Zhang, Yi-Zheng Wang, Yi-Xiao Zhai et al. · PLoS Computational Biology · 1 citation