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Author

Yang Liu

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#gene editing Open access Oct 2026

Astrocyte-Specific dsRNA–ADAR1 Signalling Links Innate Immunity to Complement Activation in Parkinson’s Disease

Astrocytes is identified as a central site of relative dsRNA accumulation and ADAR1 p150 induction in the PD cortex, and the selective coupling of dsRNA sensing to complement activation in astrocytes highlights a cell-type-specific innate immune pathway that is constitutively present rather than induced by disease.

Yang Liu, G. Halliday, Yu-Hong Fu · 0 citations

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