Structure-Based Rational Design and Synthesis of Pyridazinone Herbicides Targeting Phytoene Desaturase.
The application of herbicides plays a critical role in ensuring food security. However, the long-term overuse of herbicides can lead to a range of adverse effects. Therefore, it is essential to develop innovative and sustainable herbicides. A series of pyridazinone derivatives targeting phytoene desaturase (PDS) were d...